Congenital Hypothyroidism

Congenital Hypothyroidism

Congenital hypothyroidism is the most frequent congenital endocrine disorder and prevent‐ able cause of mental retardation. The remarkable irreversible mental damage can be avoided by the replacement therapy introduced before the age of 3 weeks. Therefore a screening program implemented in the early seventies to pick up the affected babies on the first weeks of life [1,2]. After pilot studies s...

Congenital hypothyroidism

Congenital hypothyroidism (CH) occurs in approximately 1:2,000 to 1:4,000 newborns. The clinical manifestations are often subtle or not present at birth. This likely is due to trans-placental passage of some maternal thyroid hormone, while many infants have some thyroid production of their own. Common symptoms include decreased activity and increased sleep, feeding difficulty, constipation, and...

Congenital Hypothyroidism

The thyroid forms as a midline outpouching from between the first and second pharyngeal pouches and descends into the neck just above the developing lung bud between 4 and 7 weeks gestation. The parathyroid glands condense from the third and fourth pharyngeal pouches and move into the migrated thyroid tissue. C cells are derived from separate neuroectodermal tissue in the ultimobranchial body. ...

Congenital hypothyroidism.

Congenital urogenital abnormalities in children with congenital hypothyroidism

Background: Congenital hypothyroidism (CH), as one of the most common congenital endocrine disorders, may be significantly associated with congenital malformations. This study investigates urogenital abnormalities in children with primary CH (PCH). Methods: This case-control study was conducted on 200 children aged three months to 1 year, referred to Amir-Kabir Hospital, Arak, Iran. One hund...